Acetaminophen/dichloralphenazone/isometheptene

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF) which falls under VA Drug Class CN105. This VA Drug Class (CN105) classifies this compound as belonging to the group ANTIMIGRAINE AGENTS. The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate. The European Medicines Agency schedules Acetaminophen in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB09611MIG. The World Health Organization schedules acetaminophen in its Anatomical Therapeutic Chemical (ATC) Classification. The second component of this combination drug is a sedative and hypnotic with the molecular formula C11H12N2O.2C2H3Cl3O2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier YYX637R279, chemically known as 1,2-dihydro-1,5-dimethyl-2-phenyl-3h-pyrazol-3-one, compound with 2,2,2-trichloroethane-1,1-diol (1:2) but more generally known as dichloralphenazone, which bears U.S. National Institutes of Health Compound Identifier 10188. The European Medicines Agency schedules Dichloralphenazone in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB13563MIG. The World Health Organization schedules dichloralphenazone in its Anatomical Therapeutic Chemical (ATC) Classification. The third component of this combination drug is an adrenergic agent with the molecular formula C9H19N, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier Y7L24THH6T, chemically known as 5-hepten-2-amine, n,6-dimethyl-, hydrochloride but more generally known as isometheptene, which bears U.S. National Institutes of Health Compound Identifier 22297. The European Medicines Agency schedules Isometheptene in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB08324MIG. The term ISOMETHEPTENE is an International Non-Proprietary Name or INN (see World Health Organization INN reference publication, Volume 13, No. 12, 1959, List 3). The World Health Organization schedules isometheptene in its Anatomical Therapeutic Chemical (ATC) Classification.