Voclosporin

This classification denotes an immunosuppressant with the molecular formula C63H111N11O12, a preparation that US FDA regulates as an active ingredient or moiety under Unique Ingredient Identifier 2PN063X6B1, chemically known as (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhepta-4,6-dienyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone but more generally known as voclosporin, which bears US NIH Compound Identifier 6918486. European Medicines Agency schedules Voclosporin in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB31127. The term VOCLOSPORIN is an International Non-Proprietary Name or INN (see WHO INN reference publication, Volume 22, No. 1, 2008, List 59). As of Q4 2014, VOCLOSPORIN remains US FDA's Preferred Term for this commodity. SMILES: CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC=C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C.