Tyrothricin

This classification denotes A polypeptide antibiotic mixture obtained from Bacillus brevis. It consists of a mixture of three tyrocidines (60%) and several gramicidins (20%), with the molecular formula C65H85N11O13, chemically known as 3-[(3R,6S,9S,12S,15S,17S,20S,22R,25S,28S)-20-(2-amino-2-oxoethyl)-9-(3-aminopropyl)-3,22,25-tribenzyl-15-[(4-hydroxyphenyl)methyl]-6-(2-methylpropyl)-2,5,8,11, 14,18,21,24,27-nonaoxo-12-propan-2-yl-1,4,7,10,13,16,19,23, 26-nonazabicyclo[26.3.0]hentriacontan-17-yl]propanoic acid, but generally known as tyrothricin. The term TYROTHRICIN is an International Non-Proprietary Name or INN (see WHO INN reference publication, 1955, 9, 185-194, List 1..) TYROTHRICIN is scheduled in the U.S. International Trade Commission's Harmonized Tariff System (HTS) Pharmaceutical Appendix. Most nations schedule tyrothricin under HS 29419000 and SITC 54139. SMILES: CC(C)CC1C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)NC(C(=O)C(NC(=O)C(NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN)C(C)C)CC3=CC=C(C=C3)O)CCC(=O)O)CC(=O)N)CC4=CC=CC=C4)CC5=CC=CC=C5)CC6=CC=CC=C6.