Acetaminophen/caffeine/phenylpropanolamine/pyrilamine

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF), which falls under VA Drug Class RE900. This VA Drug Class (RE900) classifies this compound as belonging to the group RESPIRATORY AGENTS, OTHER. The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate. The European Medicines Agency schedules Acetaminophen in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB09611MIG. The World Health Organization schedules acetaminophen in its Anatomical Therapeutic Chemical (ATC) Classification. The second component of this combination drug is a cns stimulant and bioactive food component with the molecular formula C8H10N4O2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 3G6A5W338E, chemically known as 1,3,7-trimethylxanthine but more generally known as caffeine, which bears U.S. National Institutes of Health Compound Identifier 2519. caffeine comes in many forms, including base, benzoate, benzoate sodium, bromide, citrate, hydrobromide, hydrochloride, hydroiodide, monohydrate, salicylate, sodium benzoate, sodium benzoicum, and sodium salicylate. The European Medicines Agency schedules Caffeine in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB13146MIG. The third component of this combination drug is an adrenergic agonist with the molecular formula C9H13NO, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 33RU150WUN, chemically known as 1r,2s-(-)-norephedrine hydrochloride but more generally known as phenylpropanolamine, which bears U.S. National Institutes of Health Compound Identifier 4786. The European Medicines Agency schedules Phenylpropanolamine in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB09790MIG. The term PHENYLPROPANOLAMINE is an International Non-Proprietary Name or INN (see World Health Organization INN reference publication, Volume 3, No. 3, 1989, List 29). The World Health Organization schedules phenylpropanolamine in its Anatomical Therapeutic Chemical (ATC) Classification. The fourth component of this combination drug is a histamine-1 receptor antagonist with the molecular formula C17H23N3O, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier HPE317O9TL, chemically known as n',n'-dimethyl-n-(p-methoxybenzyl)-n-(2-pyridyl)ethylenediamine but more generally known as pyrilamine, which bears U.S. National Institutes of Health Compound Identifier 4992.