Acetaminophen/diphenhydramine/pseudoephedrine

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF) which falls under VA Drug Class RE599. This VA Drug Class (RE599) classifies this compound as belonging to the group COLD REMEDIES, OTHER. The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate. The European Medicines Agency schedules Acetaminophen in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB09611MIG. The World Health Organization schedules acetaminophen in its Anatomical Therapeutic Chemical (ATC) Classification. The second component of this combination drug is a histamine-1 receptor antagonist and antiemetic agent with the molecular formula C17H21NO, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 8GTS82S83M, chemically known as 2-(diphenylmethoxy)-n,n-dimethylethylamine hydrochloride but more generally known as diphenhydramine, which bears U.S. National Institutes of Health Compound Identifier 3100. The European Medicines Agency schedules Diphenhydramine in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB07211MIG. The term DIPHENHYDRAMINE is an International Non-Proprietary Name. The World Health Organization schedules diphenhydramine in its Anatomical Therapeutic Chemical (ATC) Classification. The third component of this combination drug is an alpha-adrenergic agonist with the molecular formula C10H15NO, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 7CUC9DDI9F, chemically known as 1s,2s-(+)-pseudoephedrine hydrochloride but more generally known as pseudoephedrine, which bears U.S. National Institutes of Health Compound Identifier 5032. The European Medicines Agency schedules Pseudoephedrine in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB10157MIG. The term PSEUDOEPHEDRINE is an International Non-Proprietary Name or INN (see World Health Organization INN reference publication, Volume 19 1975, List 5). The World Health Organization schedules pseudoephedrine in its Anatomical Therapeutic Chemical (ATC) Classification.